13 results
L-Citrulline supplementation attenuates aortic pressure and pressure waves during metaboreflex activation in postmenopausal women
- Katherine N. Dillon, Yejin Kang, Arun Maharaj, Mauricio A. Martinez, Stephen M. Fischer, Arturo Figueroa
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- Journal:
- British Journal of Nutrition / Volume 131 / Issue 3 / 14 February 2024
- Published online by Cambridge University Press:
- 04 September 2023, pp. 474-481
- Print publication:
- 14 February 2024
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Postmenopausal women have augmented pressure wave responses to low-intensity isometric handgrip exercise (IHG) due to an overactive metaboreflex (postexercise muscle ischaemia, PEMI), contributing to increased aortic systolic blood pressure (SBP). Menopause-associated endothelial dysfunction via arginine (ARG) and nitric oxide deficiency may contribute to exaggerated exercise SBP responses. L-Citrulline supplementation (CIT) is an ARG precursor that decreases SBP, pulse pressure (PP) and pressure wave responses to cold exposure in older adults. We investigated the effects of CIT on aortic SBP, PP, and pressure of forward (Pf) and backward (Pb) waves during IHG and PEMI in twenty-two postmenopausal women. Participants were randomised to CIT (10 g/d) or placebo (PL) for 4 weeks. Aortic haemodynamics were assessed via applanation tonometry at rest, 2 min of IHG at 30 % of maximal strength, and 3 min of PEMI. Responses were analysed as change (Δ) from rest to IHG and PEMI at 0 and 4 weeks. CIT attenuated ΔSBP (−9 ± 2 v. −1 ± 1 mmHg, P = 0·006), ΔPP (−5 ± 2 v. 0 ± 1 mmHg, P = 0·03), ΔPf (−6 ± 2 v. −1 ± 1 mmHg, P = 0·01) and ΔPb (−3 ± 1 v. 0 ± 1 mmHg, P = 0·02) responses to PEMI v. PL. The ΔPP during PEMI was correlated with ΔPf (r = 0·743, P < 0·001) and ΔPb (r = 0·724, P < 0·001). Citrulline supplementation attenuates the increase in aortic pulsatile load induced by muscle metaboreflex activation via reductions in forward and backward pressure wave amplitudes in postmenopausal women.
The effect of waterfowl signals and Pseudocorynosoma enrietti infection on the behaviour of the amphipod Hyalella patagonica
- N. Figueroa, V. Flores, C. Rauque
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- Journal:
- Journal of Helminthology / Volume 97 / 2023
- Published online by Cambridge University Press:
- 31 July 2023, e62
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In the present study, we sought to determine whether i) a waterfowl signal induces avoidance behaviour of the amphipod Hyalella patagonica, ii) infection by the acanthocephalan Pseudocorynosoma enrietti affects the behaviour of the amphipod, and iii) the parasite interferes with the amphipod response to waterfowl. We evaluated amphipod behaviour experimentally by measuring activity levels, phototaxis, geotaxis, and clinging behaviour. The main findings of this study indicate that uninfected amphipods show avoidance behaviour by reducing their activity in the presence of a predator signal. Secondly, infected amphipods show altered behaviour, such as swimming in bright areas near the water surface, which makes them more visible to predators in nature. Lastly, the presence of predatory cues causes infected amphipods to drop to the bottom, which increases their visibility to predators. The present research allows us to perceive the intricate interplay among predators, parasites, and their intermediate hosts and advance our understanding of these complex ecological dynamics.
P.133 Women in Canadian neurosurgery: an update
- C Veilleux, EL Figueroa, N Samuel, H Yan, G Rosseau, M Hodaie, G Zadeh, G Milot
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- Journal:
- Canadian Journal of Neurological Sciences / Volume 50 / Issue s2 / June 2023
- Published online by Cambridge University Press:
- 05 June 2023, p. S92
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Background: Women continue to represent a minority of the neurosurgery workforce in Canada. We herein aim to provide an update of the current Canadian landscape to gain a better understanding of the factors contributing to this disparity. Methods: Chain-referral sampling, interviews, personal communications, and online resources were used as data sources. Online survey results obtained from women attending neurosurgeons across Canada were also utilized. Quantitative analyses were performed, including summary and comparative statistics. Qualitative analyses of free-text responses were performed using axial and open coding. Results: We observe a positive trend in the incoming and graduating of female residents across the country, although this trend is lagging compared to other surgical specialties. The proportion of women in active practice remains low. Positive enabling factors for success include supportive colleagues and work environment (52.6%), academic accomplishments (36.8%), and advanced fellowship training (47.4%). Perceived barriers reported included inequalities regarding career advancement opportunities (57.8%), conflicting professional and personal interests (57.8%), and lack of mentorship (36.8%). Conclusions: Women continue to represent a small proportion of practicing neurosurgeons across Canada. Our work highlights several key factors contributing to the low representation of women in neurosurgery and identifies actionable items that can be addressed by training programs and institutions.
Determination of protein–protein interactions at the single-molecule level using optical tweezers
- Wendy N. Sánchez, Luka Robeson, Valentina Carrasco, Nataniel L. Figueroa, Francesca Burgos-Bravo, Christian A. M. Wilson, Nathalie Casanova-Morales
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- Journal:
- Quarterly Reviews of Biophysics / Volume 55 / 2022
- Published online by Cambridge University Press:
- 10 August 2022, e8
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Biomolecular interactions are at the base of all physical processes within living organisms; the study of these interactions has led to the development of a plethora of different methods. Among these, single-molecule (in singulo) experiments have become relevant in recent years because these studies can give insight into mechanisms and interactions that are hidden for ensemble-based (in multiplo) methods. The focus of this review is on optical tweezer (OT) experiments, which can be used to apply and measure mechanical forces in molecular systems. OTs are based on optical trapping, where a laser is used to exert a force on a dielectric bead; and optically trap the bead at a controllable position in all three dimensions. Different experimental approaches have been developed to study protein–protein interactions using OTs, such as: (1) refolding and unfolding in trans interaction where one protein is tethered between the beads and the other protein is in the solution; (2) constant force in cis interaction where each protein is bound to a bead, and the tension is suddenly increased. The interaction may break after some time, giving information about the lifetime of the binding at that tension. And (3) force ramp in cis interaction where each protein is attached to a bead and a ramp force is applied until the interaction breaks. With these experiments, parameters such as kinetic constants (koff, kon), affinity values (KD), energy to the transition state ΔG≠, distance to the transition state Δx≠ can be obtained. These parameters characterize the energy landscape of the interaction. Some parameters such as distance to the transition state can only be obtained from force spectroscopy experiments such as those described here.
P.171 Intradural-extramedullary spinal cavernoma with nerve root association: a case report and review of the literature
- SA McQueen, F Haji, E Lucar Figueroa, Y Sallam, L Ang, N Duggal
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- Journal:
- Canadian Journal of Neurological Sciences / Volume 49 / Issue s1 / June 2022
- Published online by Cambridge University Press:
- 24 June 2022, p. S52
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Background: Although 5% of cavernomas occur in the spine, intradural-extramedullary cavernomas are exceptionally rare. We present one such case of cavernoma associated exclusively with a nerve root, and review the literature for similar lesions. Methods: Case Report. A 45-year old male patient presented with a six-month history of numbness and paresthesia affecting his lower extremities bilaterally. MRI demonstrated a 16mm intradural-extramedullary lesion at T3-4, compressing the cord. The lesion was surgically removed en-bloc, requiring root sacrifice. The patient’s symptoms completely resolved post-operatively, and he remained asymptomatic at 3-month follow up. Results: Including the present case, 71 cases of intradural-extramedullary spinal cavernoma have been reported, including 50 with confirmed nerve root involvement. Patients most frequently presented between the ages of 40-59 (41%) with lesions at the lumbar level (54%). Confirmed subarachnoid hemorrhage was present in 14% at presentation, although 23% presented acutely. 49% presented with longstanding/progressive symptoms, and 11% with mixed acute-on-chronic presentation. 37% presented primarily with radiculopathy, 21% with myelopathy, and 11% with pain. Good postoperative recovery was documented in 80% of cases. Conclusions: Intradural-extramedullary spinal cavernomas may demonstrate a propensity for radiculopathy at presentation and exhibit substantial subarachnoid hemorrhage risk. Literature review supports the role of surgical resection.
Bovine leukaemia virus DNA in fresh milk and raw beef for human consumption
- N. N. OLAYA-GALÁN, A. P. CORREDOR-FIGUEROA, T. C. GUZMÁN-GARZÓN, K. S. RÍOS-HERNANDEZ, S. P. SALAS-CÁRDENAS, M. A. PATARROYO, M. F. GUTIERREZ
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- Journal:
- Epidemiology & Infection / Volume 145 / Issue 15 / November 2017
- Published online by Cambridge University Press:
- 28 September 2017, pp. 3125-3130
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Bovine leukaemia virus (BLV) is the causative agent of enzootic bovine leucosis, which has been reported worldwide. BLV has been found recently in human tissue and it could have a significant impact on human health. A possible hypothesis regarding viral entry to humans is through the consumption of infected foodstuffs. This study was aimed at detecting the presence of BLV DNA in raw beef and fresh milk for human consumption. Nested PCR directed at the BLV gag gene (272 bp) was used as a diagnostic test. PCR products were confirmed by Sanger sequencing. Forty-nine per cent of the samples proved positive for the presence of proviral DNA. This is the first study highlighting the presence of the BLV gag gene in meat products for human consumption and confirms the presence of the viral DNA in raw milk, as in previous reports. The presence of viral DNA in food products could suggest that viral particles may also be found. Further studies are needed to confirm the presence of infected viral particles, even though the present findings could represent a first approach to BLV transmission to humans through foodstuff consumption.
The effect of AGN feedback on Sunyaev-Zeldovich properties of simulated galaxy clusters
- Dunja Fabjan, S. Planelles, S. Borgani, G. Murante, E. Rasia, V. Biffi, N. Truong, C. Ragone-Figueroa, G. L. Granato, K. Dolag, E. Pierpaoli, A. M. Beck, Lisa K. Steinborn, M. Gaspari
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- Journal:
- Proceedings of the International Astronomical Union / Volume 12 / Issue S324 / September 2016
- Published online by Cambridge University Press:
- 23 June 2017, pp. 237-238
- Print publication:
- September 2016
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We studied the imprints that feedback from Active Galactic Nuclei (AGN) leaves on the intracluster plasma during the assembly history of galaxy clusters. To this purpose we used state-of-the-art cosmological hydrodynamical simulations based on an updated version of the Tree-PM SPH GADGET-3 code, comparing three sets of simulations with different prescriptions for the physics of baryons (including AGN and/or stellar feedback). We explore the effect of these different physics, in particular AGN feedback, on IntraCluster medium (ICM) properties observed via Sunyaev-Zel’dovich (SZ) effect using an extended set of galaxy clusters (~100 clusters with M500 masses above 5 × 1013M⊙/h). Some of the main findings are that the scaling relation between the integrated SZ flux and the galaxy cluster total mass is in good accordance with several observed samples, especially for massive clusters, and does not show any clear redshift evolution, with the slope of the relation close to the theoretical one in the AGN feedback case. As for the scatter of this relation, we obtain a mild dependence on the cluster dynamical state.
Modes and instabilities in magnetized spherical Couette flow
- A. Figueroa, N. Schaeffer, H.-C. Nataf, D. Schmitt
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- Journal:
- Journal of Fluid Mechanics / Volume 716 / 10 February 2013
- Published online by Cambridge University Press:
- 25 January 2013, pp. 445-469
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Several teams have reported peculiar frequency spectra for flows in a spherical shell. To address their origin, we perform numerical simulations of the spherical Couette flow in a dipolar magnetic field, in the configuration of the $DTS$ experiment. The frequency spectra computed from time-series of the induced magnetic field display similar bumpy spectra, where each bump corresponds to a given azimuthal mode number $m$. The bumps appear at moderate Reynolds number (${\simeq }2600$) if the time-series are long enough (${\gt }300$ rotations of the inner sphere). We present a new method that permits retrieval of the dominant frequencies for individual mode numbers $m$, and extraction of the modal structure of the full nonlinear flow. The maps of the energy of the fluctuations and the spatio-temporal evolution of the velocity field suggest that fluctuations originate in the outer boundary layer. The threshold of instability is found at ${\mathit{Re}}_{c} = 1860$. The fluctuations result from two coupled instabilities: high-latitude Bödewadt-type boundary layer instability, and secondary non-axisymmetric instability of a centripetal jet forming at the equator of the outer sphere. We explore the variation of the magnetic and kinetic energies with the input parameters, and show that a modified Elsasser number controls their evolution. We can thus compare with experimental determinations of these energies and find a good agreement. Because of the dipolar nature of the imposed magnetic field, the energy of magnetic fluctuations is much larger near the inner sphere, but their origin lies in velocity fluctuations that are initiated in the outer boundary layer.
A Gaseous Group with Unusual Remote Star Formation
- N. Santiago-Figueroa, M. E. Putman, J. Werk, G. R. Meurer, E. Ryan-Weber
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- Journal:
- Publications of the Astronomical Society of Australia / Volume 28 / Issue 3 / 2011
- Published online by Cambridge University Press:
- 02 January 2013, pp. 271-279
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We present VLA 21-cm observations of the spiral galaxy ESO 481-G017 to determine the nature of remote star formation traced by an Hii region found 43 kpc and ∼800 km s−1 from the galaxy center (in projection). ESO 481-G017 is found to have a 120 kpc Hi disk with a mass of 1.2 × 1010M⊙ and UV GALEX images reveal spiral arms extending into the gaseous disk. Two dwarf galaxies with Hi masses close to 108M⊙ are detected at distances of ∼200 kpc from ESO 481-G017 and a Hi cloud with a mass of 6 × 107M⊙ is found near the position and velocity of the remote Hii region. The Hii region is somewhat offset from the Hi cloud spatially and there is no link to ESO 481-G017 or the dwarf galaxies. We consider several scenarios for the origin of the cloud and Hii region and find the most likely is a dwarf galaxy that is undergoing ram pressure stripping. The Hi mass of the cloud and Hi luminosity of the Hii region (1038.1 erg s−1) are consistent with dwarf galaxy properties, and the stripping can trigger the star formation as well as push the gas away from the stars.
Summary for Policy Makers
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- By Thomas B. Johansson, Lund University, Nebojsa Nakicenovic, International Institute for Applied Systems Analysis and Vienna University of Technology, Anand Patwardhan, Indian Institute of Technology-Bombay), Luis Gomez-Echeverri, International Institute for Applied Systems Analysis, Rangan Banerjee, Indian Institute of Technology, Sally M. Benson, Stanford University, Daniel H. Bouille, Bariloche Foundation, Abeeku Brew-Hammond, Kwame Nkrumah University of Science and Technology, Aleh Cherp, Central European University, Suani T. Coelho, National Reference Center on Biomass, University of São Paulo, Lisa Emberson, Stockholm Environment Institute, University of York, Maria Josefina Figueroa, Technical University, Arnulf Grubler, International Institute for Applied Systems Analysis, Austria and Yale University, Kebin He, Tsinghua University, Mark Jaccard, Simon Fraser University, Suzana Kahn Ribeiro, Federal University of Rio de Janeiro, Stephen Karekezi, AFREPREN/FWD, Eric D. Larson, Princeton University and Climate Central, Zheng Li, Tsinghua University, Susan McDade, United Nations Development Programme), Lynn K. Mytelka, United Nations University-MERIT, Shonali Pachauri, International Institute for Applied Systems Analysis, Keywan Riahi, International Institute for Applied Systems Analysis, Johan Rockström, Stockholm Environment Institute, Stockholm University, Hans-Holger Rogner, International Atomic Energy Agency, Joyashree Roy, Jadavpur University, Robert N. Schock, World Energy Council, UK and Center for Global Security Research, Ralph Sims, Massey University, Kirk R. Smith, University of California, Wim C. Turkenburg, Utrecht University, Diana Ürge-Vorsatz, Central European University, Frank von Hippel, Princeton University, Kurt Yeager, Electric Power Research Institute and Galvin Electricity Initiative
- Global Energy Assessment Writing Team
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- Book:
- Global Energy Assessment
- Published online:
- 05 September 2012
- Print publication:
- 27 August 2012, pp 3-30
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Summary
Introduction
Energy is essential for human development and energy systems are a crucial entry point for addressing the most pressing global challenges of the 21st century, including sustainable economic and social development, poverty eradication, adequate food production and food security, health for all, climate protection, conservation of ecosystems, peace and security. Yet, more than a decade into the 21st century, current energy systems do not meet these challenges.
A major transformation is therefore required to address these challenges and to avoid potentially catastrophic future consequences for human and planetary systems. The Global Energy Assessment (GEA) demonstrates that energy system change is the key for addressing and resolving these challenges. The GEA identifies strategies that could help resolve the multiple challenges simultaneously and bring multiple benefits. Their successful implementation requires determined, sustained and immediate action.
Transformative change in the energy system may not be internally generated; due to institutional inertia, incumbency and lack of capacity and agility of existing organizations to respond effectively to changing conditions. In such situations clear and consistent external policy signals may be required to initiate and sustain the transformative change needed to meet the sustainability challenges of the 21st century.
The industrial revolution catapulted humanity onto an explosive development path, whereby, reliance on muscle power and traditional biomass was replaced mostly by fossil fuels. In 2005, some 78% of global energy was based on fossil energy sources that provided abundant and ever cheaper energy services to more than half the people in the world.
Technical Summary
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- By Thomas B. Johansson, Lund University, Nebojsa Nakicenovic, International Institute for Applied Systems Analysis and Vienna University of Technology, Anand Patwardhan, Indian Institute of Technology, Luis Gomez-Echeverri, International Institute for Applied Systems Analysis, Doug J. Arent, National Renewable Energy Laboratory, Rangan Banerjee, Indian Institute of Technology, Sally M. Benson, Stanford University, Daniel H. Bouille, Bariloche Foundation, Abeeku Brew-Hammond, Kwame Nkrumah University of Science and Technology, Aleh Cherp, Central European University, Suani T. Coelho, National Reference Center on Biomass, University of São Paulo, Lisa Emberson, Stockholm Environment Institute, University of York, Maria Josefina Figueroa, Technical University, Arnulf Grubler, International Institute for Applied Systems Analysis, Austria and Yale University, Kebin He, Tsinghua University, Mark Jaccard, Simon Fraser University, Suzana Kahn Ribeiro, Federal University of Rio de Janeiro, Stephen Karekezi, AFREPREN/FWD, Eric D. Larson, Princeton University and Climate Central, Zheng Li, Tsinghua University, Susan McDade, United Nations Development Programme, Lynn K. Mytelka, United Nations University-MERIT, Shonali Pachauri, International Institute for Applied Systems Analysis, Keywan Riahi, International Institute for Applied Systems Analysis, Johan Rockström, Stockholm Environment Institute, Stockholm University, Hans-Holger Rogner, International Atomic Energy Agency, Joyashree Roy, Jadavpur University, Robert N. Schock, World Energy Council, UK and Center for Global Security Research, Ralph Sims, Massey University, Kirk R. Smith, University of California, Wim C. Turkenburg, Utrecht University, Diana Ürge-Vorsatz, Central European University, Frank von Hippel, Princeton University, Kurt Yeager, Electric Power Research Institute and Galvin Electricity Initiative
- Global Energy Assessment Writing Team
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- Book:
- Global Energy Assessment
- Published online:
- 05 September 2012
- Print publication:
- 27 August 2012, pp 31-94
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Summary
Introduction
Energy is essential for human development and energy systems are a crucial entry point for addressing the most pressing global challenges of the 21st century, including sustainable economic, and social development, poverty eradication, adequate food production and food security, health for all, climate protection, conservation of ecosystems, peace, and security. Yet, more than a decade into the 21st century, current energy systems do not meet these challenges.
In this context, two considerations are important. The first is the capacity and agility of the players within the energy system to seize opportunities in response to these challenges. The second is the response capacity of the energy system itself, as the investments are long-term and tend to follow standard financial patterns, mainly avoiding risks and price instabilities. This traditional approach does not embrace the transformation needed to respond properly to the economic, environmental, and social sustainability challenges of the 21st century.
A major transformation is required to address these challenges and to avoid potentially catastrophic consequences for human and planetary systems. The GEA identifies strategies that could help resolve the multiple challenges simultaneously and bring multiple benefits. Their successful implementation requires determined, sustained, and immediate action.
The industrial revolution catapulted humanity onto an explosive development path, whereby reliance on muscle power and traditional biomass was replaced mostly by fossil fuels. In 2005, approximately 78% of global energy was based on fossil energy sources that provided abundant and ever cheaper energy services to more than half the world's population.
Contributors
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- By Rose Teteki Abbey, K. C. Abraham, David Tuesday Adamo, LeRoy H. Aden, Efrain Agosto, Victor Aguilan, Gillian T. W. Ahlgren, Charanjit Kaur AjitSingh, Dorothy B E A Akoto, Giuseppe Alberigo, Daniel E. Albrecht, Ruth Albrecht, Daniel O. Aleshire, Urs Altermatt, Anand Amaladass, Michael Amaladoss, James N. Amanze, Lesley G. Anderson, Thomas C. Anderson, Victor Anderson, Hope S. Antone, María Pilar Aquino, Paula Arai, Victorio Araya Guillén, S. Wesley Ariarajah, Ellen T. Armour, Brett Gregory Armstrong, Atsuhiro Asano, Naim Stifan Ateek, Mahmoud Ayoub, John Alembillah Azumah, Mercedes L. García Bachmann, Irena Backus, J. Wayne Baker, Mieke Bal, Lewis V. Baldwin, William Barbieri, António Barbosa da Silva, David Basinger, Bolaji Olukemi Bateye, Oswald Bayer, Daniel H. Bays, Rosalie Beck, Nancy Elizabeth Bedford, Guy-Thomas Bedouelle, Chorbishop Seely Beggiani, Wolfgang Behringer, Christopher M. Bellitto, Byard Bennett, Harold V. Bennett, Teresa Berger, Miguel A. Bernad, Henley Bernard, Alan E. Bernstein, Jon L. Berquist, Johannes Beutler, Ana María Bidegain, Matthew P. Binkewicz, Jennifer Bird, Joseph Blenkinsopp, Dmytro Bondarenko, Paulo Bonfatti, Riet en Pim Bons-Storm, Jessica A. Boon, Marcus J. Borg, Mark Bosco, Peter C. Bouteneff, François Bovon, William D. Bowman, Paul S. Boyer, David Brakke, Richard E. Brantley, Marcus Braybrooke, Ian Breward, Ênio José da Costa Brito, Jewel Spears Brooker, Johannes Brosseder, Nicholas Canfield Read Brown, Robert F. Brown, Pamela K. Brubaker, Walter Brueggemann, Bishop Colin O. Buchanan, Stanley M. Burgess, Amy Nelson Burnett, J. Patout Burns, David B. Burrell, David Buttrick, James P. Byrd, Lavinia Byrne, Gerado Caetano, Marcos Caldas, Alkiviadis Calivas, William J. Callahan, Salvatore Calomino, Euan K. Cameron, William S. Campbell, Marcelo Ayres Camurça, Daniel F. Caner, Paul E. Capetz, Carlos F. Cardoza-Orlandi, Patrick W. Carey, Barbara Carvill, Hal Cauthron, Subhadra Mitra Channa, Mark D. Chapman, James H. Charlesworth, Kenneth R. Chase, Chen Zemin, Luciano Chianeque, Philip Chia Phin Yin, Francisca H. Chimhanda, Daniel Chiquete, John T. Chirban, Soobin Choi, Robert Choquette, Mita Choudhury, Gerald Christianson, John Chryssavgis, Sejong Chun, Esther Chung-Kim, Charles M. A. Clark, Elizabeth A. Clark, Sathianathan Clarke, Fred Cloud, John B. Cobb, W. Owen Cole, John A Coleman, John J. Collins, Sylvia Collins-Mayo, Paul K. Conkin, Beth A. Conklin, Sean Connolly, Demetrios J. Constantelos, Michael A. Conway, Paula M. Cooey, Austin Cooper, Michael L. Cooper-White, Pamela Cooper-White, L. William Countryman, Sérgio Coutinho, Pamela Couture, Shannon Craigo-Snell, James L. Crenshaw, David Crowner, Humberto Horacio Cucchetti, Lawrence S. Cunningham, Elizabeth Mason Currier, Emmanuel Cutrone, Mary L. Daniel, David D. Daniels, Robert Darden, Rolf Darge, Isaiah Dau, Jeffry C. Davis, Jane Dawson, Valentin Dedji, John W. de Gruchy, Paul DeHart, Wendy J. Deichmann Edwards, Miguel A. De La Torre, George E. Demacopoulos, Thomas de Mayo, Leah DeVun, Beatriz de Vasconcellos Dias, Dennis C. Dickerson, John M. Dillon, Luis Miguel Donatello, Igor Dorfmann-Lazarev, Susanna Drake, Jonathan A. Draper, N. Dreher Martin, Otto Dreydoppel, Angelyn Dries, A. J. Droge, Francis X. D'Sa, Marilyn Dunn, Nicole Wilkinson Duran, Rifaat Ebied, Mark J. Edwards, William H. Edwards, Leonard H. Ehrlich, Nancy L. Eiesland, Martin Elbel, J. Harold Ellens, Stephen Ellingson, Marvin M. Ellison, Robert Ellsberg, Jean Bethke Elshtain, Eldon Jay Epp, Peter C. Erb, Tassilo Erhardt, Maria Erling, Noel Leo Erskine, Gillian R. Evans, Virginia Fabella, Michael A. Fahey, Edward Farley, Margaret A. Farley, Wendy Farley, Robert Fastiggi, Seena Fazel, Duncan S. Ferguson, Helwar Figueroa, Paul Corby Finney, Kyriaki Karidoyanes FitzGerald, Thomas E. FitzGerald, John R. Fitzmier, Marie Therese Flanagan, Sabina Flanagan, Claude Flipo, Ronald B. Flowers, Carole Fontaine, David Ford, Mary Ford, Stephanie A. Ford, Jim Forest, William Franke, Robert M. Franklin, Ruth Franzén, Edward H. Friedman, Samuel Frouisou, Lorelei F. Fuchs, Jojo M. Fung, Inger Furseth, Richard R. Gaillardetz, Brandon Gallaher, China Galland, Mark Galli, Ismael García, Tharscisse Gatwa, Jean-Marie Gaudeul, Luis María Gavilanes del Castillo, Pavel L. Gavrilyuk, Volney P. Gay, Metropolitan Athanasios Geevargis, Kondothra M. George, Mary Gerhart, Simon Gikandi, Maurice Gilbert, Michael J. Gillgannon, Verónica Giménez Beliveau, Terryl Givens, Beth Glazier-McDonald, Philip Gleason, Menghun Goh, Brian Golding, Bishop Hilario M. Gomez, Michelle A. Gonzalez, Donald K. Gorrell, Roy Gottfried, Tamara Grdzelidze, Joel B. Green, Niels Henrik Gregersen, Cristina Grenholm, Herbert Griffiths, Eric W. Gritsch, Erich S. Gruen, Christoffer H. Grundmann, Paul H. Gundani, Jon P. Gunnemann, Petre Guran, Vidar L. Haanes, Jeremiah M. Hackett, Getatchew Haile, Douglas John Hall, Nicholas Hammond, Daphne Hampson, Jehu J. Hanciles, Barry Hankins, Jennifer Haraguchi, Stanley S. Harakas, Anthony John Harding, Conrad L. Harkins, J. William Harmless, Marjory Harper, Amir Harrak, Joel F. Harrington, Mark W. Harris, Susan Ashbrook Harvey, Van A. Harvey, R. Chris Hassel, Jione Havea, Daniel Hawk, Diana L. Hayes, Leslie Hayes, Priscilla Hayner, S. Mark Heim, Simo Heininen, Richard P. Heitzenrater, Eila Helander, David Hempton, Scott H. Hendrix, Jan-Olav Henriksen, Gina Hens-Piazza, Carter Heyward, Nicholas J. Higham, David Hilliard, Norman A. Hjelm, Peter C. Hodgson, Arthur Holder, M. Jan Holton, Dwight N. Hopkins, Ronnie Po-chia Hsia, Po-Ho Huang, James Hudnut-Beumler, Jennifer S. Hughes, Leonard M. Hummel, Mary E. Hunt, Laennec Hurbon, Mark Hutchinson, Susan E. Hylen, Mary Beth Ingham, H. Larry Ingle, Dale T. Irvin, Jon Isaak, Paul John Isaak, Ada María Isasi-Díaz, Hans Raun Iversen, Margaret C. Jacob, Arthur James, Maria Jansdotter-Samuelsson, David Jasper, Werner G. Jeanrond, Renée Jeffery, David Lyle Jeffrey, Theodore W. Jennings, David H. Jensen, Robin Margaret Jensen, David Jobling, Dale A. Johnson, Elizabeth A. Johnson, Maxwell E. Johnson, Sarah Johnson, Mark D. Johnston, F. Stanley Jones, James William Jones, John R. Jones, Alissa Jones Nelson, Inge Jonsson, Jan Joosten, Elizabeth Judd, Mulambya Peggy Kabonde, Robert Kaggwa, Sylvester Kahakwa, Isaac Kalimi, Ogbu U. Kalu, Eunice Kamaara, Wayne C. Kannaday, Musimbi Kanyoro, Veli-Matti Kärkkäinen, Frank Kaufmann, Léon Nguapitshi Kayongo, Richard Kearney, Alice A. Keefe, Ralph Keen, Catherine Keller, Anthony J. Kelly, Karen Kennelly, Kathi Lynn Kern, Fergus Kerr, Edward Kessler, George Kilcourse, Heup Young Kim, Kim Sung-Hae, Kim Yong-Bock, Kim Yung Suk, Richard King, Thomas M. King, Robert M. Kingdon, Ross Kinsler, Hans G. Kippenberg, Cheryl A. Kirk-Duggan, Clifton Kirkpatrick, Leonid Kishkovsky, Nadieszda Kizenko, Jeffrey Klaiber, Hans-Josef Klauck, Sidney Knight, Samuel Kobia, Robert Kolb, Karla Ann Koll, Heikki Kotila, Donald Kraybill, Philip D. W. Krey, Yves Krumenacker, Jeffrey Kah-Jin Kuan, Simanga R. Kumalo, Peter Kuzmic, Simon Shui-Man Kwan, Kwok Pui-lan, André LaCocque, Stephen E. Lahey, John Tsz Pang Lai, Emiel Lamberts, Armando Lampe, Craig Lampe, Beverly J. Lanzetta, Eve LaPlante, Lizette Larson-Miller, Ariel Bybee Laughton, Leonard Lawlor, Bentley Layton, Robin A. Leaver, Karen Lebacqz, Archie Chi Chung Lee, Marilyn J. Legge, Hervé LeGrand, D. L. LeMahieu, Raymond Lemieux, Bill J. Leonard, Ellen M. Leonard, Outi Leppä, Jean Lesaulnier, Nantawan Boonprasat Lewis, Henrietta Leyser, Alexei Lidov, Bernard Lightman, Paul Chang-Ha Lim, Carter Lindberg, Mark R. Lindsay, James R. Linville, James C. Livingston, Ann Loades, David Loades, Jean-Claude Loba-Mkole, Lo Lung Kwong, Wati Longchar, Eleazar López, David W. 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- Edited by Daniel Patte, Vanderbilt University, Tennessee
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- The Cambridge Dictionary of Christianity
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- 05 August 2012
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- 20 September 2010, pp xi-xliv
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Acute diarrhoeal disease in children under 7 years of age in a peri-urban slum of Santiago, Chile
- M. Araya, G. Figueroa, J. Espinoza, N. Montesinos, E. Spencer, O. Brunser
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- Journal:
- Journal of Hygiene / Volume 95 / Issue 2 / October 1985
- Published online by Cambridge University Press:
- 19 October 2009, pp. 457-467
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A group of 168 families who lived in a peri-urban slum in Santiago were surveyed for 9 months. All of them had a child under 7 years of age. Medical activities and data collection were carried out at a Field Station and by means of twice-weekly visits to each home, at which time cases of diarrhoea were recorded and investigated. Faecal samples for bacteriological, parasitological and rotavirus studies were obtained during each episode. The characteristics of clinical course, hygienic practices in the family, and monthly anthropometric measurements of infants and toddlers were also recorded. The mean monthly incidence of diarrhoea was 7·1 episodes per 100 children. Of the episodes, 44·2% were associated with pathogenic bacteria, 14·4% with rotavirus, 38·4% with parasites and in 27·9% no enteropathogens were identified. It was found that adequate hygienic habits were not associated with a decreased risk of developing diarrhoea and that about 60% of children did not have diarrhoea throughout the study period. The nutritional status was adequate in most cases: weight-for-age was below the 5th percentile in 11·5% of subjects and the height-for-age was normal in all. No moderate or severe cases of malnutrition were detected.